Milk Thistle

Also indexed as: Holy Thistle, Marian Thistle, Marythistle, Silymarin, St. Mary’s Thistle

Drug Interactions

Certain medicines interact with milk thistle: Some interactions may increase the need for milk thistle (Beneficial), other interactions may be negative (Avoid) and indicate milk thistle should not be taken without first speaking with your physician or pharmacist, others may require further explanation (Check). Refer to the individual drug article for specific details about an interaction.

Note: The following list only includes the generic or class name of a medicine. To find a specific brand name, use the Medicines index.

Acetaminophen Beneficial

Acetaminophen with Codeine Beneficial

Chemotherapy Beneficial

Cisplatin Beneficial

Clofibrate Beneficial

Fluorouracil Beneficial

General Anesthetics Beneficial

Haloperidol Beneficial

Hydrocodone with Acetaminophen Beneficial

Lovastatin Beneficial

Methotrexate Beneficial

Metronidazole Check

Nitrous Oxide Beneficial

Paclitaxel Beneficial

Pravastatin Beneficial

Tacrine Beneficial