Vardenafil

Also indexed as: Levitra

Illustration

Vardenafil is used to treat erectile dysfunction.

Summary of Interactions with Vitamins, Herbs, and Foods
In some cases, an herb or supplement may appear in more than one category, which may seem contradictory. For clarification, read the full article for details about the summarized interactions.

Avoid Avoid: Reduced drug absorption/bioavailability—Avoid these supplements when taking this medication since the supplement may decrease the absorption and/or activity of the medication in the body.

Food

Depletion or interference

None known

Side effect reduction/prevention

None known

Supportive interaction

None known

Adverse interaction

None known

An asterisk (*) next to an item in the summary indicates that the interaction is supported only by weak, fragmentary, and/or contradictory scientific evidence.

Interactions with Foods and Other Compounds

Food
A study comparing the effect of a high-fat meal and a moderate-fat meal on the absorption of vardenafil showed that taking the drug with a high-fat meal might result in a slight reduction in effectiveness and a delayed onset of action up to one hour.1

References

1. Rajagopalan P, Mazzu A, Xia C, et al. Effect of high-fat breakfast and moderate-fat evening meal on the pharmacokinetics of vardenafil, an oral phosphodiesterase-5 inhibitor for the treatment of erectile dysfunction. J Clin Pharmacol 2003;43:260–7.